Clinical Applications of Biosensors Based on Field-Effect Transistors with Carbon Nanotubes or Nanowires
Main Article Content
Abstract
In this paper we describe recent advances in the rapidly developing area of analyte detection using field-effect transistors (FETs) based on carbon nanotubes or nanowires. In this article behavior and advantages of one-dimensional nanomaterials for biosensing application is depicted. Among one-dimensional nanometer-scale materials, carbon nanotubes and nanowires offer unique electronic and mechanical properties that make them extremely attractive for the task of biosensing.
The structures and work principles of FET-biosensors based on carbon nanotubes/nanowires is discussed. Carbon nanotubes/silicon nanowire field-effect transistors have recently attracted great attention as promising tools in biosensor design because of their biocompatibility, size compatibility, ultrasensitivity, selectivity and label-free and real-time detection capabilities. In addition, interaction mechanisms between transducer elements of FET-biosensor (carbon nanotubes or nanowires) and target entities is also reviewed. Finally, applications of FET-type biosensors for measurement of different analytes is highlighted in this review. Proteins interaction, antibody–antigen reactions including prostate-specific antigen detection, DNA hybridization and enzymatic reactions involving glucose is shown.
Reference 36, figures 5.
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References
Allen, B. Carbon Nanotube Field-Effect-Transistor-Based Biosensors / B. L. Allen, P. D. Kichambare, A. Star // Advanced Materials. – 2007. – Vol. 19, June 2007. – P. 1439–1451.
Balavoine, B. Helical Crystallization of Proteins on Carbon Nanotubes: A First Step towards the Development of New Biosensors / F. Balavoine, P. Schultz, C. Richard, V. Mallouh, T.W. Ebbesen, C. Mioskowski // Angew. Chem. Int. Ed. – 1999. - Vol. 38, №13/14, P. 1912 - 1915.
Besteman, K. Enzyme-coated carbon nanotubes as single-molecule biosensors / K. Besteman, J.-O Lee, F.G.M. Wiertz, H.A. Heering, C. Dekker // Nano Letters. – 2003. – Vol. 3, №6. – P. 727–730.
Bradley, K. Charge Transfer from Ammonia Physisorbed on Nanotubes / K. Bradley, J.-C. P. Gabriel, M. Briman, A. Star, G. Grüner // Phys. Rev. Lett. – 2003. – Vol. 91, №21. – P. 218301.
Chen, K. Silicon nanowire field-effect transistor-based biosensors for biomedical diagnosis and cellular recording investigation / Kuan-I Chen , Bor-Ran Li, Yit-Tsong Chen // Nano Today. – 2011. – Vol. 6, April 2011. – P. 131–154.
Chen, R.J. Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors / R.J. Chen, S. Bangsaruntip, K.A. Drouvalakis, N.W. Kam, M.Shim, Y.M. Li, W. Kim, P.J. Utz, H.J. Dai // Proc. Natl. Acad. Sci. U. S. A. – 2003. – Vol. 100, №9. – P. 4984–4989.
Cohen-Karni, T. Graphene and nanowire transistors for cellular interfaces and electrical recording / T. Cohen-Karni, Q. Qing, Q. Li, Y. Fang, C.M. Lieber // Nano Lett. – 2010. – Vol. 10. – P. 1098–1102.
Cui, Y. Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species / Y. Cui, Q. Wei, H. Park, C.M. Lieber // Science. – 2001. – Vol. 293. – P. 1289–1292.
Curreli, M. Real-Time, Label-Free Detection of Biological Entities Using NW-Based FETs / M. Curreli, R. Zhang, F. N. Ishikawa, H.K. Chang, R.J. Cote, C. Zhou, M.E. Thompson // IEEE Transactions on nanotechnology. – 2008. – Vol. 7, №6. – P. 651–667.
Hahm, J. Direct Ultrasensitive Electrical Detection of DNA and DNA Sequence Variations Using Nanowire Nanosensors / J. Hahm, C. M. Lieber // Nano Letters. – 2004. – Vol. 4, №1, P. 51–54.
Hecht, D.S. Bioinspired Detection of Light Using a Porphyrin-Sensitized Single-Wall Nanotube Field Effect Transistor / D.S. Hecht, R.J.A. Ramirez, M. Briman, E. Artukovic, K.S. Chichak, J.F. Stoddart, G. Grüner //Nano Lett. – 2006. – Vol. 6, №9. – P. 2031–2036.
Heller, D. Optical Detection of DNA Conformational Polymorphism on Single-Walled Carbon Nanotubes / D. Heller, E. Jeng, T. Yeung, B. Martinez, A. Moll, J. Gastala, M. Strano // Science. – 2006. - Vol. 311, №5760. - P. 508-511.
Heller, D. Single-Walled Carbon Nanotube Spectroscopy in Live Cells: Towards Long-Term Labels and Optical Sensors / D. Heller, S. Baik, T. Eurell, M. Strano // Advanced Materials. – 2005. – Vol. 17, №23. – Р. 2793–2799.
Heller, I. Identifying the Mechanism of Biosensingwith Carbon Nanotube Transistors / I. Heller, A.M. Janssens, J. Mannik, E.D. Minot, S.G. Lemay, C. Dekker // Nano Lett. – 2008. –Vol. 8, №2. – P. 591–595.
Hernandez, J. Prostate-specific antigen: A review of the validation of the most commonly used cancer biomarker / J. Hernandez, I.M. Thompson // Cancer. – 2004. – Vol. 101, №5, P. 894–904.
Hu, P.A. Carbon Nanostructure-Based Field-Effect Transistors for Label-Free Chemical/Biological Sensors / P.A. Hu, J. Zhang, L. Li, Z. Wang, W. O’Neill, P. Estrela // Sensors. – 2010. – Vol. 10, №5. – P. 5133–5159.
Iijima, S. Helical microtubules of graphitic carbon / Sumio Iijima //Nature. – 1991. – Vol. 354. – P. 56–58.
Kam, N.W.S. Functionalization of Carbon Nanotubes via Cleavable Disulfide Bonds for Efficient Intracellular Delivery of siRNA and Potent Gene Silencing / N.W.S. Kam, H. Dai // J. Am. Chem. Soc. – 2005. – Vol. 127, №36, P. 12492–12493.
Kim, J.P. Ultrasensitive carbon nanotube-based biosensors using antibody-binding fragments / J.P. Kim, B.Y. Lee , S. Hong , S.J. Sim // Analytical Biochemistry. – 2008. – Vol. 381, №2. – P. 193–198.
Li, C. Complementary Detection of Prostate-Specific Antigen Using In2O3 Nanowires and Carbon Nanotubes / Chao Li, M. Curreli , H. Lin, B. Lei, F. N. Ishikawa, R. Datar, R.J. Cote, M.E. Thompson, C. Zhou // J. Am. Chem. Soc. – 2005. – Vol. 127, №36. – P. 12484–12485.
Li, J. Carbon Nanotube Nanoelectrode Array for Ultrasensitive DNA Detection / J. Li, H. T. Ng, A. Cassell, W. Fan, H. Chen, Q. Ye, J. Koehne, J. Han, M. Meyyappan // Nano Letters. – 2003. – Vol. 3, №5. – Р. 597–602.
Martel, R. Single- and multi-wall carbon nanotube field-effect transistors / T. Schmidt, H. R. Shea, T. Hertel, Ph. Avouris // Applied Physics Letters. – 1998. – Vol. 73. – P. 2447–2449.
Noy, A. Bionanoelectronics with 1D materials / A. Noy, A.B. Artyukhin, N. Misra // Materials today. – 2009. – Vol. 12, №9. – P. 22–31.
Peng, N. Sensing Mechanisms for Carbon Nanotube Based NH3 Gas Detection / N. Peng, Q. Zhang, C.L. Chow, O.K. Tan, N. Marzari // Nano Lett. – 2009. – Vol. 9, №4. – P. 1626–1630.
Poghossian, A. Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation / A. Poghossian, S. Ingebrandt, M.H. Abouzar, M.J. Schoning // Appl. Phys. A. – 2007. – Vol. 87, №3. – P. 517–524.
So, H.M. Single-Walled Carbon Nanotube Biosensors Using Aptamers as Molecular Recognition Elements / H.M. So, K. Won, Y.H. Kim, B.K. Kim, B.H. Ryu, P.S. Na, H. Kim, J.O. Lee // J. Am. Chem. Soc. – 2005. - Vol. 127, №34, P. 11906–11907.
Staii, C. DNA-Decorated Carbon Nanotubes for Chemical Sensing / C. Staii, A.T. Johnson // Nano Letters. – 2005. – Vol. 5, №9. – Р. 1774–1778.
Stern, E. Label-free biomarker detection from whole blood / E. Stern, A. Vacic, N.K. Rajan, J.M. Criscione, J. Park, B.R. Ilic, D.J. Mooney, M.A. Reed, T.M. Fahmy // Nat. Nanotechnol. – 2010. - Vol. 5, №10, P. 138-142.
Tang, X. W. Carbon Nanotube DNA Sensor and Sensing Mechanism / X.W. Tang, S. Bansaruntip, N. Nakayama, E. Yenilmez, Y.L. Chang, Q. Wang // Nano Lett. – 2006. – Vol. 6, №8. – P. 1632–1636.
Tans, S. Room-temperature transistor based on a single carbon nanotube / Sander J. Tans, Alwin R. M. Verschueren, Cees Dekker // Nature. – 1998. – Vol. 393. – P. 49–52.
Veetil, J.V. Development of Immunosensors Using Carbon Nanotubes / J.V. Veetil, K. Ye // Biotechnol Prog. – 2007. – Vol. 23, №3. – P. 517−531.
Wang, C.W. In Situ Detection of Chromogranin A Released from Living Neurons with a Single-Walled Carbon-Nanotube Field-Effect Transistor / C.W. Wang, C.Y. Pan, H.C. Wu, P.Y. Shih, C.C. Tsai, K.T. Liao, L.L. Lu, W.H. Hsieh, C.D. Chen, Y.T. Chen // Small 3. – 2007. – Vol. 3, №8, P. 1350–1355.
Wang, J. Carbon-Nanotube Based Electrochemical Biosensors: A Review / J. Wang // Electroanalysis. – 2005. – Vol. 17, №1, P. 7–14.
Wang, Y. Performance Investigation for a Silicon NW FET Biosensor Using Numerical Simulation / Y. Wang, G. Li // IEEE Nanotechnology Materials and Devices Conference. – Monterey, California (USA), 2010. – P. 81–86.
Zanello, L.P. Bone Cell Proliferation on Carbon Nanotubes / L.P. Zanello, B. Zhao, H. Hu, R. C. Haddon // Nano Letters. – 2006. – Vol. 6, №3, P. 562–567.
Zheng, G. Multiplexed electrical detection of cancer markers with nanowire sensor arrays / G. Zheng, F. Patolsky, Y. Cui, W.U. Wang, C.M. Lieber // Nature Biotechnology. – 2005. - Vol. 23, P. 1294 – 1301
