Mathematical cardiology – clinical results
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Abstract
Mathematical models, methods and means make it possible to pass from the mean statistical norms to the individual therapy. Material. Support of physician’s decision making during the acute heart failure treatment of 20000 patients from 1973 for 2010. Methods. Monitorcomputer on-line analysis in RTE. Results. The clinical-mathematical solutions for inotropic therapy of serious patients with acute heart failure which is accompanied by the spasm of the resistive vessels, and the dilation of capacitive and by other pathologies, compensating, homeostatic, etc processes are obtained. Necessity of division of pathological and adaptive reactions of patient into disease and intensive treatment is shown. The compensatory reactions of capacitive vessels to heart index reduction, the homeostatic arterial pressure stabilization with the aid of the general peripheral resistance, the protective reactions of the right ventricle, which prevent the overload of the left, and also increase the right ventricle contractility and heart rate to hypovolemia are most manifested. Conclusion. The mathematical cardiology discovers the fundamentally new possibilities of treating the acute heart failure, makes it necessary to increase the level of the mathematical disciplines teaching in the medical high schools.
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